For God so loved the world, that he gave his only begotten Son, that whosoever believeth in him should not perish, but have everlasting life.
This painting is called, The Nativity. It was painted by Gerard David, 1450-1523. It is on display at the Metropolitan Museum of Art.
And she brought forth her first born son, and wrapped him in swaddling clothes, and laid him in a manger....Luke 2:7